Born in Naples, Zingarelli studied at the Loreto Conservatory. In 1794 he succeeded Gugliemi as choir master of the Sistine Chapel in Rome. In 1816 he replaced Giovanni Paisiello as choir master of Naples cathedral. He held this position until his death. Zingarelli composed 28 masses, 41 operas, 55 Magnificats, 23 Te Deums, 20 Cantatas, 50 Symphonies and many other works.